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Guided by ultrasound, your health care provider will insert a thin, hollow needle through your stomach wall and into the uterus. A small amount of amniotic fluid is drawn into a syringe. The needle is then removed. The optimal cutoff value for urea for this study was 12.7 mg/dl. This cutoff value is comparable to 13.2 mg/dl obtained by Mohammed et al.[ 10] and 14.75 mg/dl reported by Hanfy.[ 25] However, it is higher than the 6.0 mg/dl reported by Kariman et al.[ 26] The AUC obtained from the ROC curve for urea was 50.3% (0.503). This finding is much lower when compared to the AUCs of 84% and 91% reported by Kariman et al.[ 26] and Hanfy,[ 25] respectively. The values for sensitivity, specificity, PPV, NPV, and accuracy of vaginal fluid urea level from this study was 18.8%, 95.3%, 80.0%, 54.0%, and 57.0%, respectively, while other studies were 90%, 79%, 83%, 87.5%, and 85%, respectively, by Kariman et al.,[ 26] 96% and 93%, respectively, for sensitivity and specificity of urea and 97% and 98%, respectively, for creatinine by Malchi et al.,[ 27] 100% for all the parameters by Hanfy[ 25] and Mohammed et al.[ 10]

Once PROM is confirmed, additional tests to assess the following will likely be performed to assess the following: I would use a clean glove, get some of the paper (about a 3 inch strip) and bend it over my finger. Then I would place my finger gently into the vaginal canal (careful to hold onto the strip so I don’t lose it in there).If you feel a gush of fluid, put a pad on. I then recommend laying down for 5 minutes and then getting up. If you don’t have more fluid come out at that point it is likely your water isn’t broken, but I’d still call your doctor and see what they recommend. If there is wetness, it could still be discharge, but call your provider. ACOG: Women's Healthcare Physicians [Internet]. Washington D.C.: American College of Obstetricians and Gynecologists; c2022. Amniocentesis; [reviewed 2021 Mar; cited 2022 May 9]; [about 17 screens]. Available from: https://www.acog.org/womens-health/faqs/amniocentesis

Having a family history of a genetic condition, or if the parents are carriers of a genetic condition. Besides identifying Down syndrome, amniocentesis can be used to diagnose other genetic conditions, such as cystic fibrosis.http://www.mayoclinic.org/healthy-lifestyle/pregnancy-week-by-week/expert-answers/low-amniotic-fluid/faq-20057964 The hollow needle is withdrawn again and the generated fluid and the cells it contains are processed in the laboratory. Good To Know And frankly if someone comes in saying they’re ruptured I don’t think I could “tell” if their water is broken. I just know the smell when I smell it around birth. When does Amniotic fluid leakage stop?